The answer to this question is complex and depends on how you interpret the events of Grand Theft Auto: San Andreas. While CJ's actions directly resulted in Big Smoke's death, the game doesn't explicitly portray CJ experiencing regret.
Here are some points to consider:
- CJ's Motivation: CJ's primary motivation for killing Big Smoke was revenge. Big Smoke betrayed CJ and his family, leading to the deaths of many loved ones. This fueled CJ's desire for justice and ultimately led him to confront Big Smoke.
- CJ's Reaction: While CJ shows anger and frustration towards Big Smoke throughout the game, he doesn't express any remorse or regret after killing him. He simply moves on to the next objective, seemingly unburdened by the act.
- The Game's Narrative: The game's narrative focuses on CJ's journey of revenge and redemption. His actions, including killing Big Smoke, are presented as necessary steps towards achieving these goals.
Ultimately, whether CJ regrets killing Big Smoke is left open to interpretation. The game doesn't explicitly address this question, and players are free to draw their own conclusions based on the events and characters' actions.