Ototoxicity is a serious side effect of some medications that can damage the inner ear and lead to hearing loss, tinnitus, or balance problems. While many drugs can potentially cause ototoxicity, some are more common culprits than others.
Here are some of the most common drugs that cause ototoxicity:
Antibiotics
- Aminoglycosides: These powerful antibiotics, such as gentamicin, tobramycin, and amikacin, are known for their significant ototoxic potential. They can cause both hearing loss and balance problems.
- Vancomycin: This antibiotic can also cause hearing loss, particularly when administered intravenously.
Chemotherapy Drugs
- Cisplatin: This chemotherapy drug is known to damage the inner ear, leading to hearing loss and tinnitus.
- Carboplatin: Similar to cisplatin, carboplatin can also cause ototoxicity, especially in higher doses.
Loop Diuretics
- Furosemide: This diuretic, commonly used to treat high blood pressure and fluid retention, can cause hearing loss, especially when used in high doses or for extended periods.
- Bumetanide: Similar to furosemide, bumetanide can also contribute to ototoxicity.
Other Medications
- Aspirin: While not commonly associated with ototoxicity, high doses of aspirin can cause temporary hearing loss in some individuals.
- NSAIDs: Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen can also contribute to ototoxicity, particularly when used long-term or in high doses.
It's important to note that this is not an exhaustive list, and other medications may also pose ototoxicity risks. If you are concerned about the potential for ototoxicity from a medication you are taking, consult with your doctor.
