There is no single "drug of choice" for treating all instances of MDR (multidrug-resistant). MDR can refer to different types of resistance, including:
-
Multidrug-resistant tuberculosis (MDR-TB): This is a form of tuberculosis caused by bacteria resistant to at least isoniazid and rifampin, the two most effective first-line TB drugs. Treatment for MDR-TB often involves a combination of several drugs, including:
- Bedaquiline: A new drug that targets the bacteria's energy production.
- Pretomanid: Another new drug that inhibits bacterial growth.
- Linezolid: An antibiotic that inhibits bacterial protein synthesis.
- Moxifloxacin: A fluoroquinolone antibiotic that also inhibits bacterial protein synthesis.
-
Multidrug-resistant bacteria (MDR-bacteria): This refers to bacteria that are resistant to multiple antibiotics. The specific drugs used to treat MDR-bacteria will vary depending on the specific type of bacteria involved and the antibiotics it is resistant to.
-
Other types of MDR: MDR can also occur in other infections, such as fungal infections. Treatment for these types of MDR will depend on the specific type of infection and the drugs it is resistant to.
It is crucial to consult with a healthcare professional to determine the most appropriate treatment for MDR in any given case.
