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What does JCV stand for?

Published in Medical Terminology 2 mins read

JCV stands for John Cunningham virus.

It is a type of human polyomavirus that can cause progressive multifocal leukoencephalopathy (PML), a rare and serious brain infection.

JCV is a common virus that most people are infected with at some point in their lives. It is usually harmless and remains dormant in the body.

However, in people with weakened immune systems, such as those with HIV/AIDS or undergoing certain cancer treatments, JCV can reactivate and cause PML.

PML is a serious and often fatal disease that affects the brain's white matter. It can lead to neurological problems such as vision loss, weakness, and paralysis.

Examples of JCV's impact:

  • People with weakened immune systems are at higher risk of developing PML.
  • Individuals with HIV/AIDS are particularly susceptible to JCV reactivation.
  • Certain cancer treatments, such as chemotherapy and immunosuppressants, can also increase the risk of PML.

Solutions for JCV:

  • There is no cure for PML, but antiviral medications can sometimes help slow the progression of the disease.
  • Early detection and treatment are crucial for improving outcomes.
  • Individuals with weakened immune systems should be monitored for signs and symptoms of PML.

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