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How Long Can Human Serum Be Stored?

Published in Medical Science 2 mins read

Human serum, the liquid portion of blood after clotting, can be stored for varying lengths depending on its intended use and the storage conditions.

Storage Conditions and Duration:

  • Refrigeration (2-8°C): For short-term storage, human serum can be kept refrigerated for up to 7 days.
  • Freezing (-20°C or lower): For longer storage, freezing is recommended. Human serum can be frozen for up to 1 year without significant degradation.
  • Ultra-low freezing (-80°C): For optimal preservation and long-term storage, ultra-low freezing is ideal. Serum stored at this temperature can be maintained for several years.

Factors Affecting Storage Duration:

  • Type of serum: The specific type of serum (e.g., fetal bovine serum, human serum albumin) can influence storage duration.
  • Presence of additives: Some serum preparations may contain preservatives or stabilizers that extend their shelf life.
  • Storage container: Using appropriate containers that prevent contamination and degradation is crucial for long-term storage.
  • Number of freeze-thaw cycles: Repeated freezing and thawing can damage serum components, so limiting these cycles is important.

Practical Considerations:

  • Labeling: Always label serum samples clearly with the date of collection and any relevant information.
  • Proper handling: Use sterile techniques when handling serum to prevent contamination.
  • Storage inventory: Maintain an inventory of stored serum to track expiration dates and usage.

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