Human serum, the liquid portion of blood after clotting, can be stored for varying lengths depending on its intended use and the storage conditions.
Storage Conditions and Duration:
- Refrigeration (2-8°C): For short-term storage, human serum can be kept refrigerated for up to 7 days.
- Freezing (-20°C or lower): For longer storage, freezing is recommended. Human serum can be frozen for up to 1 year without significant degradation.
- Ultra-low freezing (-80°C): For optimal preservation and long-term storage, ultra-low freezing is ideal. Serum stored at this temperature can be maintained for several years.
Factors Affecting Storage Duration:
- Type of serum: The specific type of serum (e.g., fetal bovine serum, human serum albumin) can influence storage duration.
- Presence of additives: Some serum preparations may contain preservatives or stabilizers that extend their shelf life.
- Storage container: Using appropriate containers that prevent contamination and degradation is crucial for long-term storage.
- Number of freeze-thaw cycles: Repeated freezing and thawing can damage serum components, so limiting these cycles is important.
Practical Considerations:
- Labeling: Always label serum samples clearly with the date of collection and any relevant information.
- Proper handling: Use sterile techniques when handling serum to prevent contamination.
- Storage inventory: Maintain an inventory of stored serum to track expiration dates and usage.