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What is HFpEF in Medicine?

Published in Medical Conditions 3 mins read

HFpEF stands for Heart Failure with Preserved Ejection Fraction. It's a type of heart failure where the heart's pumping function (ejection fraction) is normal, but the heart muscle is stiff and doesn't relax properly. This stiffness makes it harder for the heart to fill with blood, leading to symptoms of heart failure.

Understanding the Basics

  • Ejection Fraction: This measures how much blood the heart pumps out with each beat. A normal ejection fraction is typically 55% or higher.
  • Heart Failure: A condition where the heart can't pump blood effectively to meet the body's needs.

Why is HFpEF Different?

Unlike traditional heart failure (HFrEF), where the heart muscle is weakened and can't pump effectively, HFpEF involves a stiff heart muscle. This stiffness makes it difficult for the heart to fill with blood, even though it can still pump out the blood it receives.

Symptoms of HFpEF

Symptoms of HFpEF are similar to other types of heart failure and can include:

  • Shortness of breath: Especially during physical activity or when lying down
  • Fatigue: Feeling tired and weak
  • Fluid retention: Swelling in the legs, ankles, and feet
  • Rapid heartbeat: Often accompanied by palpitations
  • Dizziness or lightheadedness

Causes of HFpEF

The exact causes of HFpEF are still being researched, but some contributing factors include:

  • High blood pressure: Long-term high blood pressure can damage the heart muscle, leading to stiffness.
  • Diabetes: Diabetes can also damage the heart muscle and contribute to stiffness.
  • Obesity: Excess weight puts extra strain on the heart, contributing to stiffness.
  • Sleep apnea: This condition causes pauses in breathing during sleep, which can strain the heart.
  • Aging: The heart naturally becomes stiffer with age.
  • Certain medications: Some medications can also contribute to heart stiffness.

Treatment of HFpEF

Treatment for HFpEF focuses on managing symptoms and preventing further damage to the heart. This may involve:

  • Lifestyle changes: Losing weight, quitting smoking, eating a healthy diet, and getting regular exercise.
  • Medications: Diuretics to reduce fluid retention, beta-blockers to slow the heart rate, and ACE inhibitors to lower blood pressure.
  • Device therapy: In some cases, devices like pacemakers or implantable defibrillators may be used to regulate the heart rhythm.
  • Cardiac rehabilitation: A program that helps patients improve their physical fitness and learn how to manage their condition.

Conclusion

HFpEF is a complex condition that can significantly impact quality of life. Understanding the causes, symptoms, and treatment options is essential for managing this type of heart failure. Research into HFpEF is ongoing, and new treatments are continually being developed.

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