No, Sherlock Holmes did not have a sister. He was an only child, as explicitly stated in Sir Arthur Conan Doyle's stories.
While there are no known sisters in the canonical Sherlock Holmes stories, some adaptations and fan fiction have explored the idea of a sister, often adding a female character to the story.
- In the BBC series Sherlock, the character of Mycroft Holmes is portrayed as having a sister, but this is not part of the original canon.
- In some fan fiction, Sherlock Holmes is given a sister who is either a fellow detective or a supporting character.
However, in the original stories by Sir Arthur Conan Doyle, Sherlock Holmes is an only child.
