This question is a bit ambiguous! It could be asking about:
1. Presidents of the United States who died in office:
- William Henry Harrison (1841): Died 31 days into his term from pneumonia.
- Zachary Taylor (1850): Died 16 months into his term from an unknown illness, possibly cholera.
- Abraham Lincoln (1865): Assassinated by John Wilkes Booth on April 15, 1865.
- James A. Garfield (1881): Assassinated by Charles J. Guiteau on July 2, 1881.
- William McKinley (1901): Assassinated by Leon Czolgosz on September 14, 1901.
- Warren G. Harding (1923): Died from a heart attack while on a trip to Alaska.
- Franklin D. Roosevelt (1945): Died from a cerebral hemorrhage on April 12, 1945.
- John F. Kennedy (1963): Assassinated by Lee Harvey Oswald on November 22, 1963.
2. Other world leaders who died in office:
- Julius Caesar (44 BC): Assassinated by Roman senators.
- Queen Elizabeth I (1603): Died from natural causes.
- King George V (1936): Died from a heart attack.
- Winston Churchill (1965): Died from a stroke.
- Nelson Mandela (2013): Died from a lung infection.
3. People who died in office, regardless of their position:
- This could refer to anyone who died while holding a job, from a CEO to a teacher.
To get a more precise answer, you could add more context to your question. For example:
- "Who died early in office as President of the United States?"
- "Who died early in office from natural causes?"
- "Who died early in office due to political assassination?"
Understanding the specifics of your question will help you find the most relevant answer.