B3 deficiency, also known as pellagra, is a condition that occurs when your body doesn't get enough niacin (vitamin B3). This can lead to a variety of symptoms, including:
Common Symptoms:
- Dermatitis: This is a skin rash that often appears on areas exposed to sunlight. It may be red, scaly, and itchy.
- Diarrhea: This is a common symptom of B3 deficiency, and it may be accompanied by abdominal pain and cramping.
- Dementia: This is a more serious symptom that can occur if B3 deficiency is left untreated. It can lead to confusion, memory loss, and difficulty concentrating.
- Other Symptoms: Other possible symptoms include fatigue, headache, dizziness, and loss of appetite.
Causes of B3 Deficiency:
- Poor Diet: A diet that is low in niacin-rich foods can lead to B3 deficiency.
- Alcoholism: Excessive alcohol consumption can interfere with the body's ability to absorb niacin.
- Certain Medical Conditions: Some medical conditions, such as Hartnup disease and carcinoid syndrome, can increase the risk of B3 deficiency.
- Medications: Certain medications, such as isoniazid, can interfere with niacin absorption.
Treatment:
B3 deficiency is usually treated with niacin supplements. The dosage will vary depending on the severity of the deficiency. In severe cases, hospitalization may be necessary to receive intravenous niacin.
It is important to note that B3 deficiency is preventable. Eating a healthy diet that includes niacin-rich foods can help to reduce your risk.