This question doesn't have a single, universal answer as "closest" can be interpreted in different ways. It could refer to:
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Genetically Closest: Your identical twin is your closest blood relative genetically. You share 100% of your DNA with an identical twin.
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Legally Defined Closest: The term "closest blood relative" often comes up in legal contexts, like inheritance or medical decisions. In these cases, "next of kin" is the legally defined term. It usually refers to your spouse, children, parents, or siblings depending on local laws and specific circumstances.
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Emotionally Closest: Your closest blood relative might be the one you feel the strongest emotional connection to. This is subjective and depends on your individual relationships and experiences.
It's important to consider the context and the specific definition of "closest" when answering this question.