No, Tom and Jerry is not based on a true story. It is a fictional animated series created by William Hanna and Joseph Barbera.
The characters of Tom and Jerry were originally conceived as part of a series of short films called "Tom and Jerry Cartoons," produced by Metro-Goldwyn-Mayer (MGM) from 1940 to 1958.
While the series has been incredibly popular and beloved for generations, there is no real-life inspiration for the cat and mouse duo. The characters and their interactions are entirely fictional, designed to create humorous and entertaining situations.
The creators of Tom and Jerry drew inspiration from classic comedic duos like Laurel and Hardy and the Three Stooges, as well as popular cartoons of the time. They combined elements of slapstick comedy, physical humor, and witty dialogue to create a unique and enduring series.
The popularity of Tom and Jerry has led to numerous adaptations, spin-offs, and merchandise over the years, solidifying its place as one of the most iconic animated franchises in history.